Counting Cherry Reduction Sequences in Phylogenetic Tree-Child Networks is Counting Linear Extensions.

Orchard and tree-child networks share an important property with phylogenetic trees: they can be completely reduced to a single node by iteratively deleting cherries and reticulated cherries. As it is the case with phylogenetic trees, the number of ways in which this can be done gives information about the topology of the network. Here, we show that the problem of computing this number in tree-child networks is akin to that of finding the number of linear extensions of the poset induced by each network, and give an algorithm based on this reduction whose complexity is bounded in terms of the level of the network.

Antiparkinsonian Medication Reconciliation as a Strategy to Improve Safety by Preventing Medication Errors.

Background: About 70% of neurologists report that PD patients do not get their medication properly when hospitalized, and 33% are prescribed contraindicated drugs.

Objectives: To execute medication reconciliation (MedRec) focused on antiparkinsonian drugs to identify, characterize and, eventually, prevent medication errors, thus promoting therapeutic quality and safety in daily practice.

Methods: An interventional, single-center, 1 year, prospective study.

Mild SARS-CoV-2 infection in vulnerable patients: implementation of a clinical pathway for early treatment.

Introduction: The objective of this report is to describe the clinical pathway for early treatment of patients with acute SARS-CoV-2 infection and to evaluate the first results of its implementation.

Methods: This is a descriptive and retrospective study of the implementation of a clinical pathway of treatment in outpatients (January 1 to June 30 2022). Clinical pathway: detection and referral systems from Primary Care, Emergency services, hospital specialities and an automated detection system; clinical evaluation and treatment administration in the COVID-19 day-hospital and subsequent clinical follow-up.