Publications by authors named "G Jagadeesan"

Article Synopsis
  • Stroke is a leading cause of long-term disability and poses a significant financial burden on global healthcare, with recovery largely influenced by ischemic injury and systemic inflammation.
  • The study tested the effects of cromolyn, a mast cell stabilizer, on neuroinflammation and stroke outcomes using a mouse model, leading to reduced mast cell numbers in the brain and improved functional outcomes despite no significant differences in infarct volume.
  • Results showed that cromolyn treatment decreased plasma histamine and IL-6 levels while also reducing gut mast cell numbers, suggesting that mast cell activity and trafficking are important factors in stroke recovery.
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Inhibition of breakdown of dietary carbohydrates, by controlling the postprandial activity of diabetic enzymes through fruit polyphenolics can help downregulate the effects of Type 2 Diabetes Mellitus (T2DM). The study focuses on deciphering the induction of hyperglycaemic control by bio-accessed anti-oxidative polyphenols of Cucumic dipsaceus fruits. Chiefly, we examined the antioxidant activity of bio-accessed polyphenols of C.

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Ethnopharmacological Relevance: An annual herb, Ipomoea pes-tigridis L. (Convolvulaceae) is widely used for its anti-inflammatory and anti-spasmodic properties in traditional medicine. As well as treating wounds, fever, skin disorders, and other ailments, it is also used for other purposes.

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Miliusa nilagirica, a rare tree species of Western Ghats, belongs to the Annonaceae family, a family with potential antioxidant and antidiabetic properties. This study is designed vividly to establish the relationship between the constituent phytochemicals and their hyperglycemic effects through the antioxidant traits of M. nilagirica in vitro.

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A rich source of nutrients, figs have a number of clinically validated benefits. This study aimed to evaluate the in vitro simulated gastrointestinal digestion, and the antidiabetic and anticancer activity of (FMP) and (FRP) fruits polysaccharides. The pre-digested FMP revealed higher sugar content (721 ± 14.

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