Increased GABBR2 Expression on Cell Membranes Causes Increased Ca2 + Inward Flow, Associated with Cognitive Impairment in Early Alzheimer's Disease.

Alzheimer's disease (AD) and mild cognitive impairment (MCI) are a serious global public health problem. The aim of this study was to analyze the key molecular pathological mechanisms that occur in early AD progression as well as MCI. Expression profiling data from brain homogenates of 8 normal volunteers, and 6 patients with prodromal AD who had developed MCI were analyzed, and the data were obtained from GSE12685.

Global research trends and frontiers in ferroptosis in hepatocellular carcinoma: a bibliometric and visualization study.

Background: Since the emergence of the hot topic of "ferroptosis," numerous studies have explored its role in hepatocellular carcinoma (HCC), revealing its significance in the disease's pathogenesis, progression, and treatment. However, there remains a significant gap in the quantitative analysis of ferroptosis in HCC. Therefore, this study aims to comprehensively assess the research progress and evolution in this field through bibliometric and citation analysis.

Clinical features, risk factors, outcomes, and prediction model for intrahepatic and perihepatic abscess following hepatectomy for hepatocellular carcinoma.

Background: Intrahepatic and perihepatic abscess (IPHA) is a severe yet understudied complication that can occur after hepatectomy. This multicenter study aimed to elucidate the clinical features, risk factors, and outcomes of IPHA after hepatectomy for hepatocellular carcinoma (HCC), and to develop a novel prediction model for personalized risk assessment.

Methods: This was a multicenter cohort study of HCC patients who underwent curative-intent hepatectomy.

Strategy To Enhance Interfacial Properties: Preparation of Porous Polytetrafluoroethylene Fibers and the Adsorption of Initiators/Curing Agents.

Polytetrafluoroethylene (PTFE) fibers exhibit high inertness and demonstrate limited interfacial bonding capabilities with other materials. To overcome this limitation, PTFE@ZnO fibers were developed by depositing the porous ZnO layer onto PTFE fibers via a hydrothermal reaction, and porous fibers were adsorbed curing agents or initiators. The interfacial shear strength (ILSS) of the composites demonstrated a significant improvement, particularly in the case of composites containing PTFE/initiator fibers, where the ILSS increased by 104.

One-Pot Synthesis of Multicentric DIL@PDIL Catalyst for Mild CO 2 Conversion to Cyclic Carbonates.

Among the various studies on CO2 utilization, the sustainable and cost-effective fixation of CO2 into cyclic carbonates remains one of the most intriguing subjects. To this end, a novel type of  composite dicationic ionic liquid material, DIL@PDIL, was developed. This composite consists of a dicationic ionic liquid (DIL), DMAP[TMGH]Br, supported on a polymeric dicationic ionic liquid (PDIL), P-DVB/Im[TMGH]Br.