Publications by authors named "G J Velat"

Aneurysms that involve the internal carotid artery and posterior communicating artery junction and incorporate a fetal posterior cerebral artery are known as fetal posterior communicating artery aneurysms. We report the outcomes of four patients with fetal posterior communicating artery aneurysms who underwent treatment with the pipeline embolization device with or without adjunctive coil embolization. In our study, all four patients failed to achieve aneurysm occlusion at the last follow-up evaluation.

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Article Synopsis
  • A small percentage of cerebral aneurysms rupture, causing severe effects, and current management options include surgery, endovascular treatments, or monitoring. Understanding the biology behind aneurysm growth and rupture could lead to new preventative drugs.
  • The study involved examining human and mouse aneurysms to investigate the role of stromal cell-derived factor-1 (SDF-1) in the inflammation that affects aneurysm walls, using methods like immunohistochemistry and flow cytometry.
  • Results showed SDF-1 was present in aneurysms and played a role in the migration of endothelial cells and macrophages, promoting capillary formation; blocking SDF-1 in mice resulted in fewer endothelial cells in
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Background: Untreated, moyamoya angiopathy is a progressive vaso-occlusive process that can lead to ischemic or hemorrhagic stroke.

Objective: To review 1 institution's surgical experience with both direct and indirect bypass (encephaloduroarteriosynangiosis) in adult and pediatric groups.

Methods: A retrospective review was conducted of a consecutive series of patients treated for moyamoya angiopathy between 1995 and 2009.

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Background: The pipeline embolization device (PED) is the latest technology available for intracranial aneurysm treatment.

Objective: To report early postmarket results with the PED.

Methods: This study was a prospective registry of patients treated with PEDs at 7 American neurosurgical centers subsequent to Food and Drug Administration approval of this device.

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Introduction: Over the past several decades, checklists have emerged in a variety of different patient care settings to help reduce medical errors and ensure patient safety. To date, there have been no published accounts demonstrating the effectiveness of checklists designed specifically for the unique demands of neurointerventional procedures.

Methods: A three-part, 20-item checklist was developed specific to neurointerventional procedures using the WHO surgical checklist as a template.

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