Arginine Regulates the Mucoid Phenotype of Hypervirulent .

Hypervirulent is associated with severe community-acquired infections. Hypervirulent colonies typically exhibit a mucoid phenotype. mucoidy is influenced by a complex combination of environmental factors and genetic mechanisms.

Fourth-year Student Pharmacists' Perceptions of a Required Student-run Free Clinic Experience.

Objective: The University of Michigan Student-Run Free Clinic (UMSRFC) provides quality preventive, acute, and chronic care free of charge to uninsured and underinsured community members. We sought to assess fourth-year student pharmacists' (P4) attitudes toward providing care as part of a required experience at the UMSRFC during their Ambulatory Care Advanced Pharmacy Practice Experience.

Methods: All P4s in the 2023-2024 academic year completed an 8-hour experience at the UMSRFC.

Sensory Ecology, Bioeconomy, and the Age of COVID: A Parallax View of Indigenous and Scientific Knowledge.

Drawing on original ethnobotanical and anthropological research among Indigenous peoples across the Amazon, we examine synergies and dissonances between Indigenous and Western scientific knowledge about the environment, resource use, and sustainability. By focusing on the sensory dimension of Indigenous engagements with the environment-an approach we have described as "sensory ecology" and explored through the method of "phytoethnography"-we promote a symmetrical dialogue between Indigenous and scientific understandings around such phenomena as animal-plant mutualisms, phytochemical toxicity, sustainable forest management in "multinatural" landscapes, and the emergence of new diseases like the novel coronavirus SARS-CoV-2 (COVID-19). Drawing examples from our own and other published works, we explore the possibilities and limitations of a "parallax view" attempting to hold Indigenous and scientific knowledge in focus simultaneously.

VPS45 is required for both diffuse and tip growth of cells.

Introduction: VPS45 belongs to the Sec1/Munc18 family of proteins, which interact with and regulate Qa-SNARE function during membrane fusion. We have shown previously that VPS45 interacts with the SYP61/SYP41/VTI12 SNARE complex, which locates on the -Golgi network (TGN). It is required for SYP41 stability, and it functions in cargo trafficking to the vacuole and in cell expansion.

Global importance of Indigenous Peoples, their lands, and knowledge systems for saving the world's primates from extinction.

Primates, represented by 521 species, are distributed across 91 countries primarily in the Neotropic, Afrotropic, and Indo-Malayan realms. Primates inhabit a wide range of habitats and play critical roles in sustaining healthy ecosystems that benefit human and nonhuman communities. Approximately 68% of primate species are threatened with extinction because of global pressures to convert their habitats for agricultural production and the extraction of natural resources.