Side Effects of Novel Anticancer Drugs on the Posterior Segment of the Eye: A Review of the Literature.

Currently, common treatment approaches for neoplastic diseases include surgery, radiation, and/or anticancer drugs (chemotherapy, hormone medications, and targeted therapies). In particular, anticancer medicines destroy cancerous cells by blocking certain pathways that aid in the disease's initiation and progression. These pharmaceutical drugs' capacity to inhibit malignant cells has made them indispensable in the treatment of neoplastic disorders.

Assessment of plasma resolvin levels in women with breast cancer and their associations with disease presentation and immunohistochemical characteristics.

Background: Resolvins, which are divided into series D (RvD) and E (RvE), originate from omega-3 fatty acids, DHA and EPA and were recently found to be involved in the modulation of inflammation in some tumors, including breast cancer (BC). We aimed to assess the resolvin profiles (RvD1, RvD2, RvD3 and RvE1) in the plasma of BC patients compared with those of controls and to determine differences in their concentrations according to BC presentation and immunohistochemical characteristics.

Methods: We considered BC patients (sporadic, familiar and BRCA1/2-mutated forms) naïve to any anticancer treatment and controls affected by nonmalignant breast disease.

Antennal olfactory responses in the black soldier fly Hermetia illucens.

The Black Soldier Fly (BSF) is considered as the "crown jewel" of the insect feed industry and circular economy, significantly contributing to the 2030 Sustainable Development Goals by reducing carbon dioxide emissions and enabling circular management of organic waste, animal manure, and plant residues. Despite their industrial importance, limited knowledge about adult BSF biology has hindered optimal mass production. In this context, the present paper aims to explore the olfactory capabilities of both male and female BSF in response to various odorants commonly associated with organic decomposition in substrates suitable for mate encounters and egg laying.

Iron deficiency anemia in pregnancy and the postpartum: a practical approach by the Italian GOAL Working Group.

Background: Iron deficiency and iron deficiency anemia represent global health issues, particularly during pregnancy and the postpartum. The present paper aims to summarize the appropriate management of these conditions in order to try to improve how clinicians perceive, diagnose and treat iron deficiency and iron deficiency anemia.

Methods: An expert panel of Italian obstetricians of Lazio region was convened to evaluate the available literature on iron deficiency and iron deficiency anemia during pregnancy and the post-partum in order to try to define a flow chart on the appropriate management of such conditions; aspects related to the patient blood management have also been investigated.

High topological charge lasing in quasicrystals.

Photonic modes exhibiting a polarization winding akin to a vortex possess an integer topological charge. Lasing with topological charge 1 or 2 can be realized in periodic lattices of up to six-fold rotational symmetry-higher order charges require symmetries not compatible with any two-dimensional Bravais lattice. Here, we experimentally demonstrate lasing with topological charges as high as -5, +7, -17 and +19 in quasicrystals.