Publications by authors named "G J M McDougall"
Impairment of gut barrier integrity is associated with the pathogenesis of gastrointestinal diseases, including inflammatory bowel disease, colorectal cancer, and coeliac disease. While many aspects of diet have been linked to improved barrier function, (poly)phenols, a broad group of bioactive phytochemicals, are of potential interest. The (poly)phenolic sub-class, flavan-3-ols, have been investigated in some detail owing to their abundance in commonly consumed foods, including grapes, tea, apples, cocoa, berries, and nuts.
View Article and Find Full Text PDFArticle Synopsis
- * The phytochemicals in honey, including flavonoids and phenolic acids, demonstrate a variety of beneficial properties like anti-inflammatory, antiaging, and antioxidant effects relevant to skin health.
- * While current studies show promise for honey's potential in treating dermatological disorders, further high-quality research is needed to confirm its clinical efficacy as a bioactive agent or cosmeceutical.
Article Synopsis
- A systematic review was conducted to compare video laryngoscopy (VL) and direct laryngoscopy (DL) for intubating critically ill adult patients in emergency and ICU settings.
- The analysis included 20 randomized controlled trials and found that VL likely improves first pass success rates and reduces the likelihood of esophageal intubations compared to DL.
- Additionally, VL may lead to fewer dental injuries and aspiration events, with no significant difference in mortality rates between the two methods.
Age-associated decline of nuclear factor erythroid 2-related factor 2 (Nrf2) activity and DNA repair efficiency leads to the accumulation of DNA damage and increased risk of cancer. Understanding the mechanisms behind increased levels of damaged DNA is crucial for developing interventions to mitigate age-related cancer risk. Associated with various health benefits, (poly)phenols and their microbially mediated phenolic catabolites represent a potential means to reduce DNA damage.
View Article and Find Full Text PDFWith the growing global population and climate change, achieving food security is a pressing challenge. Vertical farming has the potential to support local food production and security. As a Total Controlled Environment Agriculture (TCEA) system, vertical farming employs LED lighting which offers opportunities to modulate light spectrum and intensity, and thus can be used to influence plant growth and phytochemical composition, including antioxidants beneficial for human health.
View Article and Find Full Text PDF