Publications by authors named "G J Kramer"

Article Synopsis
  • The study examines the impact of immediate breast reconstruction (IBR) on the quality of life for breast cancer patients in the Netherlands over the past decade.
  • Findings show a significant increase in IBR usage for both ductal carcinoma in situ (DCIS) and invasive breast cancer, with positive associations linked to patient age and treatment factors.
  • Despite the overall rise in IBR, there are notable differences in its application among various hospitals, prompting further research to address these disparities.
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Background And Objective: Prostate-specific antigen (PSA) is of limited value as a surrogate marker for overall survival (OS) in prostate cancer (PC). Serum thymidine kinase 1 (sTK1) is an enzyme expressed by actively dividing cells. Our aim was to evaluate the value of sTK1 as prognostic biomarker in metastatic hormone-sensitive PC (mHSPC) and metastatic castration-resistant PC (mCRPC).

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The xCures platform aggregates, organizes, structures, and normalizes clinical EMR data across care sites, utilizing advanced technologies for near real-time access. The platform generates data in a format to support clinical care, accelerate research, and promote artificial intelligence/ machine learning algorithm development, highlighted by a clinical decision support algorithm for precision oncology.

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Two experiments investigated proactive facilitation (PF) or proactive interference (PI) in the recall of recently learned targets, under conditions of assessing the detection and recollection of target changes across two learning phases (with A-B/A-D word pairs). Some changes established meaningful connections across the phases; others did not. Task instructions on the subsequent cued-recall test (Experiment 1) or during Phase 2 study (Experiment 2) guided participants (university students) to monitor and report the changes.

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