Tranexamic acid for preventing postpartum haemorrhage after vaginal birth.

Rationale: Postpartum haemorrhage (PPH) is common and potentially life-threatening. The antifibrinolytic drug tranexamic acid (TXA) is thought to be effective for treating PPH. There is growing interest in whether TXA is effective for preventing PPH after vaginal birth.

Tranexamic acid for preventing postpartum haemorrhage after caesarean section.

Rationale: Postpartum haemorrhage (PPH) is common and potentially life-threatening. The antifibrinolytic drug tranexamic acid (TXA) is recommended for treating PPH; it reduces the risk of death from haemorrhage by one-third when given soon after bleeding onset, but not overall risk of death. Interest in whether TXA may be effective in preventing PPH is growing.

Posterior lower uterine segment caesarean hysterotomy, an innovative surgical technique to avoid classical hysterotomy: Case report and discussion.

A 40-year-old patient underwent laparotomy at term gestation for a 25-cm lower abdominal mass arising from the lateral wall of the uterus, with an extensive secondary blood supply from the lower uterus and bladder, preventing access to the anterior lower uterine segment. The gravid uterus was exteriorised over the patient's thighs. A transverse posterior lower uterine segment hysterotomy was performed and a healthy 2920 g baby was delivered.

Development and Piloting of Implementation Strategies to Support Delivery of a Clinical Intervention for Postpartum Hemorrhage in Four sub-Saharan Africa Countries.

Introduction: Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality. A new clinical intervention (E-MOTIVE) holds the potential to improve early PPH detection and management. We aimed to develop and pilot implementation strategies to support uptake of this intervention in Kenya, Nigeria, South Africa, and Tanzania.