Publications by authors named "G J Hageman"

We present a method for identifying, classifying, and distinguishing unresolved reflective objects. A forward model is developed to predict how the radiance field from a specular surface will be angularly distributed and how samples detected from that field can be used to infer surface profile characteristics. We present lab studies to validate the forward model and demonstrate unresolved object identification and classification.

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Article Synopsis
  • * Research indicates that levels of IRAK-M decrease with age and oxidative stress, with genetic variants linked to a higher risk of developing AMD.
  • * Restoring IRAK-M in RPE cells shows promise in protecting against oxidative damage and retinal degeneration, indicating it could be a potential therapeutic avenue for AMD.
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Purpose: The purpose of this study was to determine if levels of the HtrA1 protein in serum or vitreous humor are influenced by genetic risk for age-related macular degeneration (AMD) at the 10q26 locus, age, sex, AMD status, and/or AMD disease severity, and, therefore, to determine the contribution of systemic and ocular HtrA1 to the AMD disease process.

Methods: A custom-made sandwich ELISA assay (SCTM ELISA) for detection of the HtrA1 protein was designed and compared with three commercial assays (R&D Systems, MyBiosource 1 and MyBiosource 2) using 65 serum samples. Concentrations of HtrA1 were thereafter determined in serum and vitreous samples collected from 248 individuals and 145 human donor eyes, respectively.

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Aerotoxic Syndrome may develop as a result of chronic, low-level exposure to organophosphates (OPs) and volatile organic compounds in the airplane cabin air, caused by engine oil leaking past wet seals. Additionally, acute high-level exposures, so-called "fume events," may occur. However, air quality monitoring studies concluded that levels of inhaled chemicals might be too low to cause adverse effects.

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