Publications by authors named "G J Friedrich"

Background: Children with sickle cell disease (SCD) have increased stroke risk, identifiable by elevated velocities on transcranial Doppler (TCD). This review assessed the impact of TCD screening on stroke, mortality, quality of life and morbidity in children with SCD.

Methods: A systematic search of MEDLINE, PubMed, Cochrane libraries, and trial registries was conducted from inception to 28th February 2023.

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Background: Detection of sickle cell disease (SCD) could be improved with greater use of point-of-care testing (POCT). This review assessed the accuracy of POCTs for SCD in children and adolescents.

Methods: We systematically searched EMBASE, PubMed, Cochrane libraries, registries and conference proceedings from inception to 28th February 2023.

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Article Synopsis
  • - Myocardial revascularization, either through percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery, effectively alleviates symptoms and enhances quality of life when paired with guideline-directed medical therapy.
  • - Hybrid coronary revascularization is a combination approach that employs CABG for the left anterior descending artery (LAD) and PCI for other coronary vessels, targeting patients who are not ideal candidates for traditional CABG.
  • - The procedure is best performed in a collaborative setting with a specialized heart team, focusing on complete revascularization, particularly in patients with complex multivessel coronary disease, leveraging advanced drug-eluting stents.
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Objectives: Public campaigns such as the "Go-red-for-women"-initiative have raised heart-disease awareness and may trigger overutilization of coronary computed tomography angiography (CTA). Objective was to investigate the diagnostic efficacy of coronary CTA stratified by age and gender.

Methods: 1882 consecutive patients (58.

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