Publications by authors named "G J Botto"
Background: The subcutaneous implantable cardioverter-defibrillator (S-ICD) is an alternative to traditional ICDs. The PRAETORIAN score, based on chest radiographs, has been validated to predict the probability of successful S-ICD defibrillation testing by assessing factors like fat thickness between the coil and sternum and generator placement.
Objective: This study evaluated the correlation between the PRAETORIAN score and clinical characteristics, as well as implantation variables.
Article Synopsis
- The HeartInsight multiparametric algorithm uses remote monitoring data from implantable cardioverter-defibrillators (ICDs) to calculate an HF Score, which helps predict worsening heart failure hospitalizations (WHFHs).
- A study pooled data from 9 clinical trials involving 1,841 ICD patients, finding that a high baseline HF Score significantly correlates with increased long-term risks of death and WHFHs.
- The analysis revealed that patients with an HF Score over 23 faced more than double the risk of experiencing death or WHFH compared to those with lower scores, emphasizing the score's potential in risk stratification for heart failure patients.
Background: Enhanced characterization of the atrial electrical substrate may lead to better comprehension of atrial fibrillation (AF) pathophysiology.
Objective: With the use of high-density substrate mapping, we sought to investigate the occurrence of functional electrophysiological phenomena in the left atrium and to assess potential association with arrhythmia recurrences after catheter ablation.
Methods: Sixty-three consecutive patients with AF referred for ablation were enrolled.
Article Synopsis
- Subclinical atrial fibrillation (AF) increases risks of developing clinical AF, stroke, and cardiovascular death; researchers aimed to test if closed loop stimulation (CLS) could reduce atrial high-rate episodes (AHREs) in pacemaker patients compared to conventional dual-chamber rate-adaptive pacing (DDDR).
- A study with 1,210 patients showed that those using CLS had a lower incidence of the primary endpoint (first AHRE lasting ≥6 min, stroke, or TIA) compared to DDDR over a 3-year period, particularly effective in patients without atrioventricular block or AF history.
- The findings suggest that dual-chamber CLS significantly reduces AHRE occurrence, highlighting its potential benefits for patients
Background: Frailty and comorbidity influence the therapeutic approach in everyday clinical practice. The DOACs genericization opens a reflection on their differences from a pharmacological and bioavailability point of view, particularly in elderly frail patients. The aim of this project was to create a national Delphi consensus on the topic of the use of DOACs for atrial fibrillation (AF) in such patients, in light of the genericization of the class.
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