Publications by authors named "G J Beilman"
Background: Venous waveform analysis is an emerging technique to estimate intravascular fluid status by fast Fourier transform deconvolution. Fluid status has been shown proportional to , the amplitude of the fundamental frequency of the waveform's cardiac wave upon deconvolution. Using a porcine model of distributive shock and fluid resuscitation, we sought to determine the influence of norepinephrine on of the central venous waveform.
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- Unpredictable reactions to sedatives and analgesics in critically ill patients on mechanical ventilation may stem from genetic differences.
- The study aimed to explore the relationship between pharmacogenomic variations and sedation outcomes, while also assessing ICU patients' views on pharmacogenomic testing.
- The researchers found that while participants showed a median of 2 altered pharmacogenomic phenotypes, there were no significant links between these genetic variations and sedation effectiveness; however, ICU patients generally had positive attitudes towards pharmacogenomic testing.
Objectives: Clinical management of traumatic brain injury (TBI) focuses on preventing secondary injury from cerebral edema and ongoing anoxic injury. Consensus guidelines recommend maintaining systolic blood pressure (SBP) 110 mmHg. A recent prehospital study suggested lowest adjusted mortality from 130 mmHg to 180 mmHg, suggesting the ideal pressure may be higher.
View Article and Find Full Text PDFAlterations in the gut microbiome have been implicated in various pathologies. Fecal microbiota transplantation (FMT) has been offered as a novel treatment for conditions implicated in the disruption of the gut-microbiota axis. This case report details the successful treatment of recurrent nonobstructive cholangitis following a single FMT application in a patient who had previously undergone a hepatobiliary tract surgical diversion.
View Article and Find Full Text PDFBackground: Low titer group O whole blood (LTOWB) is commonly used for severe bleeding in trauma patients. LTOWB may also benefit young children requiring cardiac surgery with cardiopulmonary bypass (CPB) at risk of severe bleeding.
Study Design And Methods: In this retrospective study, children <2 years old who underwent cardiac surgery with CPB were included.