Publications by authors named "G Iodice"
Article Synopsis
- - The study aimed to analyze the psychosocial status of a large adult population and its connection to Temporomandibular Disorders (TMD), oral behaviors, and self-reported facial trauma, moving beyond previous studies that mostly examined treatment-seeking patients.
- - A sample of 4,299 adults (1,700 males and 2,599 females with an average age of 40.4) was randomly recruited from public spaces; assessments included mental health questionnaires and TMD symptom evaluations, revealing significant rates of psychosocial impairment and chronic pain.
- - Results indicated that mental health issues like anxiety and depression were notably linked to gender, TMD pain, and certain behaviors; additionally, TMD symptoms and pain disability correlated
Article Synopsis
- - Research on patients with normal pressure hydrocephalus (NPH) indicates that early Alzheimer's disease (AD) pathology can be detected, and this study aims to identify cerebrospinal fluid (CSF) biomarkers related to these initial AD changes.
- - The study analyzed CSF data and found that specific biomarkers such as β-amyloid-42/40 and neurofilament light chain (NfL) are correlated with AD pathology; seven key proteins were identified that also relate to both pathology and gene expression.
- - The findings suggest a link between CSF biomarkers and central nervous system changes in AD, providing valuable insights into how these markers reflect the disease's progression.
Psychometric properties of patient-reported outcomes Common Terminology Criteria for adverse events (PRO-CTCAE®) in breast cancer patients: The prospective observational multicenter VIP study.
Breast
October 2024
Patients' self-reporting is increasingly considered essential to measure quality-of-life and treatment-related side-effects. However, if multiple patient-reported instruments are used, redundancy may represent an overload for patients. Patient-Reported Outcomes Common Terminology Criteria for Adverse Events (PRO-CTCAE) are a tool allowing direct patients' reporting of side-effects.
View Article and Find Full Text PDFIntroduction: Normal pressure hydrocephalus (NPH) patients undergoing cortical shunting frequently show early AD pathology on cortical biopsy, which is predictive of progression to clinical AD. The objective of this study was to use samples from this cohort to identify CSF biomarkers for AD-related CNS pathophysiologic changes using tissue and fluids with early pathology, free of post-mortem artifact.
Methods: We analyzed Simoa, proteomic, and metabolomic CSF data from 81 patients with previously documented pathologic and transcriptomic changes.
Introduction: The aim of this in vitro study was to examine the potential impact of different curing times of 3D-printed orthodontic aligners on their cytotoxicity.
Method: Some 60 samples of aligner material were directly 3D printed using Tera Harz TC-85 DAC resin and randomly allocated to three different curing time groups (14, 24 and 50 min). Zendura FLX samples were used as control.