The incidence of small for gestational age neonates in singleton IVF pregnancies.

Introduction: Various factors related to an "" fertilization (IVF) procedure may influence the rate of small for gestational age (SGA) newborns in such pregnancies.

Aim: The aim of the study was to determine neonatal SGA incidence in singleton IVF pregnancies compared to spontaneous ones.

Materials And Methods: We conducted both a prospective and a retrospective study within the period of January 2013-December 2017, which included 336 patients with a singleton IVF pregnancy at the time of delivery - the study group (SG), and 493 women with a spontaneous conception - the control group (CG).

[Oocyte quality as a predictive marker for assessment of IVF/ICSI procedure outcome].

The technology of in vitro fertilization consists mainly of pick up, selection and insemination of oocytes, embryo culture and their transfer into recipient's womb. Before any further manipulation of oocytes their quality has to be accurately evaluated as it has direct impact on the monospermic fertilization, early development, establishment and maintenance of pregnancy. Criteria applied for oocyte quality assessment are subdivided into morphological, cellular and molecular.

[In vitro maturation--a potential approach of infertility treatment of patients with PCOS].

Polycystic ovary syndrome (PCOS) affects about 15-20% of women of reproductive age. This is a heterogeneous condition characterized by a combination of menstrual cycle disturbances, hyperandrogenism and polycystic ovaries. A significant percent of these women comes to the necessity of assisted reproduction procedure.

[Endocrinology of in vitro maturation of oocytes].

In-vitro maturation (IVM) of oocytes is an alternative to conventional in-vitro fertilization (IVF) treatment. Significant progress has been made to improve pregnancy and implantation rates from in-vitro matured oocytes. However oocyte maturation in vitro is profoundly affected by culture conditions.