Publications by authors named "G Illuminati"
Aims: To analyze the long-term results of a prospective phase II trial testing intensified total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer (LARC).
Materials And Methods: Patients with histologically confirmed LARC adenocarcinoma were enrolled. Intensified TNT consisted of targeted agent (bevacizumab or panitumumab/cetuximab) plus FOLFOXIRI (5-fluorouracil, leucovorin, oxaliplatin and irinotecan) induction chemotherapy followed by intensified (oxaliplatin and 5-fluorouracil) chemoradiotherapy (CRT) and surgical resection.
: Giant splenic artery aneurysms (SAAs) and pseudoaneurysms (SAPs) represent rare conditions, characterized by a diameter greater than or equal to 5 cm. The risk of rupture is increased compared to common SAAs and SAPs, necessitating urgent treatments to prevent it. : This systematic review was conducted through a comprehensive search involving the PubMed, Google Scholar, and Scopus databases.
View Article and Find Full Text PDFArticle Synopsis
- The combined approach of performing percutaneous coronary intervention (PCI) and endovascular aneurysm repair (EVAR) simultaneously offers a new treatment option for patients with both coronary artery disease and aortic aneurysms, addressing a significant gap in cardiovascular care.
- A study involved seven patients who underwent this dual procedure while monitoring various complications and effectiveness; the main focus was on intraoperative and postoperative complications, with length of procedure and recovery times as secondary metrics.
- Postoperative results showed minor complications like acute renal failure in chronic patients, but there were no significant issues like cardiac or limb ischemia, with an average procedure time of 198 minutes and fluoroscopy time of about 41.7 minutes.
Late type II endoleaks (T2ELs) arising from the internal iliac artery (IIA) may present during follow-up after endovascular aortic repair (EVAR) of aortoiliac aneurysm and may warrant embolization if enlargement of the aneurysmal sac is demonstrated. When coverage of the IIA ostium has been made due to extensive iliac disease, access options can be challenging. Different treatment options have been reported over recent years, and a careful selection of the best one must be made based on the characteristics of each case.
View Article and Find Full Text PDFBackground: Cardiovascular and renal diseases represent a major determinant for the morbidity and mortality associated with obesity and type 2 diabetes mellitus (T2DM). Bariatric surgery is considered one of the few treatments with the potential to reverse cardiovascular, renal and metabolic disease.
Methods: Prospective study of patients undergoing sleeve gastrectomy collecting pre- and post-surgery creatinine, eGFR, glucose, insulin, total, LDL/HDL cholesterol, triglycerides, parathyroid hormone, vitamin D3, C- Reactive Protein (CRP), blood count, weight, body mass index (BMI), bilateral carotid intima media thickness (IMT), flow-mediated dilation (FMD) and epicardial adipose tissue (EAT).