[The characteristics of the analgesic action of nitrosorbide and no-shpa].

The study was conducted on experimental models of pain sense induced in mice by exposure to thermic or chemical factors and in rats by exposure to electric factors. Nitrosorbide and no-spa possess a dose-dependent analgesic effect. Both drugs excelled analgin in the intensity and duration of analgesic effect.

[The effect of euphylline on the antimicrobial activity of antibiotics].

Antimicrobic properties of euphylline as well as its effects on antibacterial activity of penicillins, cephalosporins, and aminoglycosides were studied. It was established that euphylline differently affects antimicrobic activity of aforementioned drugs.

[A morphological assessment of the efficacy of benzofurocaine in experimental burns].

Studies of the effect of benzophurocaine on the morphological structure of the skin and viscera in animals with burn disease have shown the drug to have a protective action. The latter one manifested itself in a considerable reduction of injuries to the viscera and in a more rapid recovery of the disordered structure and function.

[Comparative evaluation of the wound-healing effect of benzofuracaine, etaden, and xanthinol nicotinate in an experiment].

The effect of benzofuracaine, etaden, and xanthinol nicotinate on the healing of skin wounds was studied in rat experiments. On days 1-14 of postmechanical injury, intramuscular benzofuracaine (15, 30, 60, and 120 mg/kg), etaden (20 mg/kg), and xanthinol nicotinate (each drug alone) reparative processes in the skin wounds developed more rapidly and processes of microcirculation in the region of the injury were normalized. The wound-healing effect of benzofurocaine in an ortimal dose of 60 mg/kg was more marked than that op etaden and xanthinol nicotinate.

[Effects of benzofurocaine, etaden and xanthinol nicotinate on reparative bone regeneration in animal experiments].

In the process of treatment of experimental close fractures of radius in rats by intramuscular administration of benzofurocaine (60 mg/kg), the regeneration processes of the bone tissue were activated to a greater degree than in case of administration of etadene (20 mg/kg) or xanthinol nicotinate (30 mg/kg). Under the influence of benzofurocaine, beginning on the 10-20-th day of the experiment, there have been noted the reorganization of young callus into the mature laminal bone. The preparations of comparison have demonstrated less expressed analogous action.