Publications by authors named "G I Sirota"

Objective: Machine learning algorithms have shown groundbreaking results in neuroimaging. Herein, the authors evaluate the performance of a newly developed convolutional neural network (CNN) to detect and quantify the thickness, volume, and midline shift (MLS) of subdural hematoma (SDH) from noncontrast head CT (NCHCT).

Methods: NCHCT studies performed for the evaluation of head trauma in consecutive patients between July 2018 and April 2021 at a single institution were retrospectively identified.

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  • - Vitamin D is crucial for calcium and phosphate regulation, but its impact on fetal bone strength remains uncertain; this study examined the connection between maternal 25(OH)D levels and neonatal bone strength in 81 mother-infant pairs using quantitative ultrasound.
  • - The research found that while maternal and cord blood 25(OH)D levels were strongly correlated, with cord blood levels being higher, there was no significant link between maternal vitamin D levels and neonatal bone strength or growth indicators.
  • - Additionally, certain demographic factors influenced maternal vitamin D levels, with Jewish mothers having higher levels than Muslim mothers; however, bone strength (measured as speed of sound in tibial bones) remained similar across different maternal vitamin D status groups.
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  • * Using near-infrared spectroscopy, researchers measured regional oxygen saturation (rSOS) before and after each feeding method in 21 infants under 32 weeks gestation.
  • * Results show that continuous feeding lowers rSOS compared to bolus feeding, but it does not significantly affect the oxygen extraction by the intestines; there was also a slight trend towards reduced systemic oxygen levels after bolus feeding.
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  • The study aimed to assess how blood transfusions affect iron status and other related parameters in stable preterm infants.
  • Researchers analyzed data from 63 preterm infants before and within 24 hours after receiving red blood cell transfusions, measuring factors like hemoglobin, ferritin, hepcidin, and erythropoietin.
  • Results showed an increase in hemoglobin and ferritin post-transfusion, while hepcidin levels also rose, indicating that preterm infants can regulate their iron levels influenced by their age.
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  • The study examined the impact of a twice daily exercise program on bone strength in very low birth weight (VLBW) preterm infants compared to once daily and no exercise interventions.
  • Thirty-four VLBW infants were randomly placed into three groups for a four-week period, where they underwent assisted range-of-motion exercises starting shortly after birth.
  • Results showed that while bone strength declined in all groups, those in the twice daily intervention experienced a significantly reduced decrease in bone strength, suggesting benefits for preventing osteopenia and fractures.
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