[Individual characteristics of water-mineral metabolism during 120-day head-down tilt hypokinesia and the effectiveness of prophylactic measures].

Sodium balance and circulating plasma, intracellular, extracellular and interstitial fluid volumes were measured in the test subjects exposed for 120 days to head-down tilt at -5 degrees. The large scatter of the above parameters was associated with individual variations and with the use of different countermeasures against demineralization (exercise and drugs-xydiphone and glucamak). The effect of the countermeasures was different both in qualitative and quantitative terms.

[Body position of the human during hypokinesia and water-salt metabolism].

Two groups of 5 healthy volunteers each were exposed for 7 days to: 1) group 1 to horizontal bed rest and 2) group 2 to head-down tilt at -6 degrees. The purpose of the study was to determine the effect of body position on fluid-electrolyte metabolism and renal function. During the control period (14 days), bed rest and the recovery period the consumption of fluids and mineral substances and their renal excretion were measured.

[Effect of hypoxia on water-electrolyte metabolism and human renal function with different degrees of motor activity].

It was demonstrated that a prolonged (24 days) bed rest at altitudes of 2200 m and 3200 m as well as at sea level was accompanied by an increased renal excretion of fluids and osmotically active substances, including electrolytes. Exercises done during bed rest indiced a smaller increase of the renal excretion of sodium and potassium. However, as bed rest continued the differences between the groups of test subjects disappeared.

[Water-salt metabolism in members of the crew of Saliut-4].

The paper presents the results of studying the fluid-electrolyte metabolism in P. I. Klimuk and V.