[Bipolar and monopolar affective disorders of juvenile age].

Results of clinico-psychopathological and clinico-catamnestic studies are presented based on the examination of 174 patients with affective disorders that manifested themselves at the age of 15-25 years. The main psychopathological features of juvenile phase-affective conditions are described (subtle vital manifestations of the thymic component, polymodality of the affect with simultaneous presentation of two varieties of affective disorders, instability of the affect changing within a single phase, high occurrence of overvalued ideas reflecting specific emotions of the juvenile age with concomitant manifestations of pubertal psychological crisis underlain by common pathogenetic mechanisms). High frequency of mixed affective conditions and the predominance of the bipolar type of the disease are emphasized, clinical features of mono- and bipolar pathology are described.

[Clinical-genetic parameters and the nosological evaluation of schizoaffective psychosis in systematics of attack-like endogenous psychoses].

Authors studied 1013 first- and second degree relatives in families of 193 probands. The probands were stratified by clinical diagnosis into 6 groups: 1) nuclear variant of schizoaffective psychosis (SAP); 2) "marginal" (intermediate) variant of SAP; 3) schizoaffective variant of schizophrenia; 4) recurrent schizophrenia; 5) attack-like progressive schizophrenia; 6) bipolar affective disorder or manic-depressive psychosis (MDP). Probands (n=109) and their relatives were studied using the direct clinical examination; the study of 84 probands and their relatives was based on the medical records from the genetic archive of Mental Health Research Center, Russian Academy of Medical Sciences.

[Mixed affective states in the juvenile age (historical aspects, current state of the problem, psychopathology)].

The author analyzed the problem in historical, diagnostic and psychopathological aspects and presented the results of his own study. The aim was to study the structure and dynamics of endogenous juvenile mixed states in order to work out the psychopathological typology and to clarify the criteria of diagnosis, differential treatment and clinical-social prognosis. The study included 174 patients, 118 men and 56 women, aged from 17 to 25 years (mean age 20, 4 years).

[Contribution of pubertal psychobiological processes to the formation and clinical manifestations of juvenile depressions].

Based on the study of 486 patients, aged from 16 to 25 years, key features of psychopathology of juvenile depressions were specified. They included bluntness and atypism of a depressive triad with insignificant expression and rudimentariness of the thymic component per se, a large proportion of cognitive disorders and psychopathy-like disturbances, a higher frequency of special overvalued syndromes of metaphysical and dysmorphophobic character. Types of juvenile depressions were singled out as follows: depressions with the clinical picture of juvenile asthenic failure, dysmorphophobic, metaphysical, heboid, psychasthenic-like, depersonalization, senestho-hypochondriac depressions as well as depressions with obsessive-phobic disorders and with "psychogenic contents".