Publications by authors named "G Holmvang"
Article Synopsis
- The study investigates the connection between ventricular arrhythmias and myocardial fibrosis in patients with mitral valve prolapse (MVP), focusing on how valve mechanics may contribute to these conditions.
- Researchers analyzed 113 patients using echocardiograms and cardiac MRI to measure fibrosis and left ventricular function, finding that those with fibrosis experienced worse mitral regurgitation and specific abnormal strain patterns.
- Over a follow-up period, they discovered that about 41% of patients with MVP and myocardial fibrosis developed ventricular arrhythmias, suggesting a link between mechanical abnormalities and arrhythmic events.
This JACC Scientific Expert Panel provides consensus recommendations for an update of the cardiovascular magnetic resonance (CMR) diagnostic criteria for myocardial inflammation in patients with suspected acute or active myocardial inflammation (Lake Louise Criteria) that include options to use parametric mapping techniques. While each parameter may indicate myocardial inflammation, the authors propose that CMR provides strong evidence for myocardial inflammation, with increasing specificity, if the CMR scan demonstrates the combination of myocardial edema with other CMR markers of inflammatory myocardial injury. This is based on at least one T2-based criterion (global or regional increase of myocardial T2 relaxation time or an increased signal intensity in T2-weighted CMR images), with at least one T1-based criterion (increased myocardial T1, extracellular volume, or late gadolinium enhancement).
View Article and Find Full Text PDFBackground: We sought to evaluate the effect of application of the revised 2010 Task Force Criteria (TFC) on the prevalence of major and minor Cardiovascular Magnetic Resonance (CMR) criteria for Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) versus application of the original 1994 TFC. We also assessed the utility of MRI to identify alternative diagnoses for patients referred for ARVC evaluation.
Methods: 968 consecutive patients referred to our institution for CMR with clinical suspicion of ARVC from 1995 to 2010, were evaluated for the presence of major and minor CMR criteria per the 1994 and 2010 ARVC TFC.
Aims: Prior work has demonstrated that magnetic resonance imaging (MRI) strain can separate necrotic/stunned myocardium from healthy myocardium in the left ventricle (LV). We surmised that high-resolution MRI strain, using navigator-echo-triggered DENSE, could differentiate radiofrequency ablated tissue around the pulmonary vein (PV) from tissue that had not been damaged by radiofrequency energy, similarly to navigated 3D myocardial delayed enhancement (3D-MDE).
Methods And Results: A respiratory-navigated 2D-DENSE sequence was developed, providing strain encoding in two spatial directions with 1.