Publications by authors named "G Hejblum"
Background And Aims: The economic impact of managing patients with hepatitis C virus (HCV) infection remains unknown. This study aimed to assess the economic burden of chronic HCV infection from a national health insurance perspective and the impact of direct-acting antivirals (DAAs) using nationwide real-world data.
Methods: Patients with chronic HCV infection were identified from the French Health Insurance Claims Databases (SNDS) and matched for age and sex to the general population.
During the pandemic period, health care systems were substantially reorganized for managing COVID-19 cases. Corresponding consequences on persons with chronic diseases remain insufficiently documented. This observational cohort study investigated the direct and indirect impact of the pandemic period on the survival of kidney transplant recipients (KTR).
View Article and Find Full Text PDFThe validity of algorithms for identifying patients with chronic hepatitis B or C virus (HBV or HCV) infection in claims databases has been little explored. The performance of 15 algorithms was evaluated. Data from HBV- or HCV-infected patients enrolled between August 2012 and December 2015 in French hepatology centres (ANRS CO22 HEPATHER cohort) were individually linked to the French national health insurance system (SNDS).
View Article and Find Full Text PDFPurpose: The impact of direct-acting antivirals (DAAs) on extrahepatic complications in chronic hepatitis C (CHC) patients remains poorly described. We estimated the association of DAAs with cardiovascular events and extrahepatic cancers.
Methods: The prospective ANRS CO22 HEPATHER cohort was enriched with individual data until December 2018 from the French Health Insurance Database (SNDS).
Article Synopsis
- A significant drop in hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) was noted in France during the first two years of the COVID-19 pandemic, with monthly admissions decreasing from 8,899 to 6,032.
- The study found that in-hospital mortality for AECOPD increased from 6.2% to 7.6%, indicating worse outcomes for patients hospitalized during the pandemic.
- The data suggest that only a small percentage of AECOPD hospital stays were linked to COVID-19, but those with COVID-19 had nearly three times the mortality rate compared to those without it.