What approaches exist to evaluate the effectiveness of UK-relevant natural flood management measures? A systematic map.

Background: This systematic map principally sought to understand the different forms of effectiveness that existing studies evaluate in relation to Natural Flood Management (NFM) in the UK with a supplementary question of whether studies engaged with climate change and future flood risk. NFM measures seek to protect, enhance, emulate, or restore the natural function of rivers as part of approaches to flood risk management (FRM). While there is agreement in both academic and practice/policy literature that NFM should be part of a holistic FRM strategy to address current and future flood risk, the specifics of how to expand the application of and consistently implement NFM successfully in practice are less well known.

Volcanic-Tectonic Structure of the Mount Dent Oceanic Core Complex in the Ultraslow Mid-Cayman Spreading Center Determined From Detailed Seafloor Investigation.

The flanks of the ultraslow-spreading Mid-Cayman Spreading Center (MCSC) are characterized by domal massifs or oceanic core complexes (OCCs). The most prominent of these, Mount Dent, comprises lower-crustal and upper-mantle lithologies and hosts the Von Damm vent field ~12 km west of the axial deep. Here, presented autonomous underwater vehicle-derived swath sonar (multibeam) mapping and deep-towed side-scan sonar imagery lead to our interpretation that: (i) slip along the OCC-bounding detachment fault is ceasing, (ii) the termination zone, where detachment fault meets the hanging wall, is disintegrating, (iii) the domed surface of the OCC is cut by steep north-south extensional faulting, and (iv) the breakaway zone is cut by outward facing faults.

IgG2a and igA co-expression by the natural autoantibody-producing murine B lymphoma T560.

The T560 B lymphoma produces polyreactive IgG2a with the features of natural autoantibody. All T560 cells bear and secrete IgG2a but a small fraction spontaneously co-express IgA. Cells secreting IgA alone cannot be detected.

The IgG2a/IgA produced by the murine T560 B lymphoma that arose during a graft-versus-host reaction is polyreactive and somatically mutated.

In mice undergoing a graft-versus-host (GVH) reaction, donor T cells responding to the host's MHC antigens induce polyclonal activation of the host's B cells and secretion of their antibodies and autoantibodies. T560, a CD5- B lymphoma that arose in the gut-associated lymphoid tissue (GALT) of a (B10 x B10.H2aH4(b)pWts) F1 hybrid mouse that had been injected with parental B10.