Publications by authors named "G Harada"
Article Synopsis
- - The study developed a nomogram to predict the likelihood of pelvic lymph node metastases (ypN+) after neoadjuvant chemotherapy in nonmetastatic muscle-invasive bladder cancer patients, finding that ypN+ is linked to worse overall survival.
- - Data from 6,194 patients were analyzed, revealing that 22.8% of high-risk patients had ypN+, compared to only 8.0% in the low-risk group, with high-risk patients experiencing significantly shorter survival (36.1 vs. 74.0 months).
- - Key factors contributing to the nomogram included age, time from diagnosis to treatment, and the tumor’s histology and stage, making it a valuable tool for assessing risk
Purpose: TRK fusions are detected in less than 2% of central nervous system tumors. There are limited data on the clinical course of affected patients.
Experimental Design: We conducted an international retrospective cohort study of patients with TRK fusion-driven CNS tumors.
Article Synopsis
- Enfortumab vedotin (EV) and pembrolizumab (P) are standard treatments for advanced urothelial carcinoma, and this study investigates the safety of combining EV with radiation therapy (RT).
- The study involved nine patients who received EV and RT simultaneously, focusing on the side effects of radiation and symptom relief.
- Results showed that adverse effects were mostly mild, with significant symptom relief achieved; further research is suggested for broader conclusions.
Introduction: This study investigates the impact of pre- and post-treatment hematologic markers, specifically neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), on treatment outcomes in soft tissue sarcoma (STS) patients undergoing radiation therapy (RT).
Methods: Data from 64 patients who underwent RT for curative management of STS were reviewed. Pre-RT and post-RT hematologic measures were evaluated for associations with survival outcomes.