Publications by authors named "G Hackl"
Article Synopsis
- In rare cases, patients who are intoxicated may need extracorporeal procedures to help remove toxins from their bodies more effectively.
- The EXTRIP workgroup provides updated guidelines based on evidence and consensus for using these procedures in critically ill, poisoned patients.
- The best results for toxin removal occur with substances that have specific properties, and intermittent hemodialysis is the most effective method, while continuous procedures are better for patients with compromised blood flow.
Article Synopsis
- A study analyzed 581 cases of acute poisoning admitted to a medical ICU in Austria from 2007 to 2021, revealing that suicidal intent was the primary cause in nearly half of the cases and that 46.6% involved mixed intoxications.
- The research utilized various data sources, including ICU records and autopsy reports, and found that while ICU mortality was low at 4.1%, pre-existing psychiatric illnesses had increased significantly among patients over time.
- Compared to a historical dataset from 1992-1996, there was a notable shift away from gastric lavage as a detoxification method and a rise in alternative techniques, indicating changes in treatment approaches for intoxicated patients.
Introduction: Soluble urokinase plasminogen activator receptor (suPAR) is a biologically active protein and increased levels are associated with worse outcomes in critically ill patients. suPAR in bronchoalveolar fluid (BALF) may be helpful to differentiate between types of acute respiratory distress syndrome (ARDS) and may have potential for early detection of fungal infection.
Methods: We prospectively investigated levels of suPAR in BALF and serum in critically ill patients who underwent bronchoscopy for any reason at the ICU of the Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Article Synopsis
- Carbohydrate-deficient transferrin (CDT) and the Anttila-Index are biomarkers that may indicate heavy alcohol use and could predict delirium and mortality in critically ill patients.
- In a study of 343 ICU patients, 35% experienced delirium, with those affected showing significantly higher levels of CDT and Anttila-Index upon admission.
- Higher CDT and Anttila-Index levels were linked to both the occurrence of delirium and longer duration of delirium, as well as increased hospital mortality risk.