Clinical Manifestations.

Background: Similar neuroimaging abnormalities are reported in post-COVID patients and patients with AD. Moreover, COVID-19 and Alzheimer's Disease (AD) share genetic vulnerabilities and have similar cognitive symptoms of COVID (e.g.

Clinical Manifestations.

Background: Semantic memory assessments are sensitive indicators of cognitive decline in pre-clinical Alzheimer's Disease (AD), with slowed reaction time and diminished accuracy serving as markers for amyloid accumulation. We introduce the Semantic Stroop Test-a brief (4.3 minute), automated semantic retrieval and executive function task included in the California Cognitive Assessment Battery (CCAB).

Clinical Manifestations.

Background: The administration of cognitive tests in patients' homes facilitates access by underserved communities and increases testing capacity and efficiency. However, the validity of at-home computerized cognitive tests is often questioned because of limitations in examiner monitoring, distractions, environmental noise, and potential cheating. Here, we compare performance of the computerized and proctored California Cognitive Assessment Battery (CCAB) when administered at-home or in the laboratory using otherwise identical procedures.

The distribution and severity of lower-limb hypertonicity and spasticity differentially impacts walking speed in people with neurological injuries.

Purpose: To investigate the relationship between the distribution and severity of hypertonicity and spasticity on walking speed in people with neurological injuries.

Material/methods: This cross-sectional observation cohort study used the Modified Ashworth Scale (MAS) and Modified Tardieu Scale (MTS) to assess hypertonicity and spasticity of the gastrocnemius, soleus, hamstrings and quadriceps. Participants were classified as having a distal (gastrocnemius and/or soleus), proximal (hamstrings and/or quadriceps) or mixed distribution of hypertonicity or spasticity.

Earlier diagnosis of small intestine neuroendocrine tumours (SI-NETs) through transformation of the South Wales NET service.

Small intestine neuroendocrine tumours (SI-NETs) are often diagnosed late with a UK median of 3 years and high misdiagnosis rates. Previous studies, largely based on patient surveys, offer little data on improving diagnosis. In 2017, the South Wales NET service underwent a nationally commissioned, systematic transformation, aiming to improve diagnosis through the development of a gastroenterology and surgical referral network, and education of these specialities.