Publications by authors named "G H Visser"
We present a resonant-mode, transverse-field, radio-frequency (rf) neutron spin flipper design that uses high-temperature superconducting films to ensure sharp transitions between uniform magnetic field regions. Resonant mode allows for low-power, high-frequency operation but requires strict homogeneity of the magnetic fields inside the device. This design was found to efficiently flip neutrons at 96.
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- - The study evaluates how the quality of MRI scans (specifically signal-to-noise ratio and spatial resolution) affects the detection of focal cortical dysplasia (FCD) using a software called Morphometric Analysis Program v2018 (MAP18) in patients with epilepsy.
- - Researchers conducted a retrospective analysis on 30 MRI scans and artificially reduced the SNR and SR, discovering that lower quality led to significant declines in detecting FCD clusters and their characteristics.
- - The findings indicate that low-quality MRI scans can hinder FCD detection, suggesting that ensuring high-quality imaging is crucial before conducting further analysis, as missing FCD can lead to ongoing seizures.
Monocyte and macrophage profiles in patients with inherited long-chain fatty acid oxidation disorders.
Biochim Biophys Acta Mol Basis Dis
January 2025
Patients with inherited disorders of the long-chain fatty acid oxidation (lcFAO) machinery present with a heterogeneous profile of disease manifestations and aggravation of symptoms is often triggered by inflammatory activation. Monocytes and macrophages are innate immune cells that play a major role in the onset and resolution of inflammation. These cells undergo metabolic rewiring upon activation including the regulation of the FAO rate.
View Article and Find Full Text PDFThis narrative review provides an overview of the current knowledge on health-related quality of life (HRQOL), a relevant clinical outcome in patients with epilepsy. It shows that the most important factor determining HRQOL in this patient group is seizure frequency. In particular, seizure-freedom is associated with better HRQOL scores.
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