Publications by authors named "G H Ring"
Article Synopsis
- Cardiovascular health in young people can reduce the risk of heart disease later in life and enhance physical and cognitive abilities as they age.
- This study examined high school students' physical activity levels, comparing those with a sports-focused curriculum to their peers regarding physical and cognitive performance and arterial stiffness.
- Findings indicated that male students with extracurricular sports activities showed improved cognitive skills, while females in a sports curriculum performed better in running, and male students displayed lower arterial stiffness, suggesting a connection between sports involvement and better cardiovascular health.
Introduction: Adulteration of illicit drugs is a well-known phenomenon that may expose consumers to unexpected adverse effects. We report a large outbreak of severe coagulopathy in northern Israel during nine months in 2021-2022 among users of synthetic cannabinoids adulterated with a long-acting anticoagulant, brodifacoum.
Methods: We performed a retrospective cohort study based on data extracted from the Israeli National Poison Information Center database and from electronic medical patient records at three participating hospitals.
Article Synopsis
- Knowledge of element concentrations in botanical extracts is important for consumer safety, especially with the rise in popularity of plant-based ingredients, as this study offers a detailed metallomic profile of several plant extracts for the first time.
- Using a validated HR-ICP-SFMS method, a wide range of key elements was quantified in various plants, revealing significant variability in their concentrations, but none exceeded permissible health limits.
- The study concluded that while high consumption of certain plants could pose a potential health risk due to cumulative exposure to specific metals, overall risks were minimal under normal intake rates, supporting further research into the quality and safety of botanical ingredients.
A method has been developed, optimised and validated to analyse protein powder supplements on an inductively coupled plasma-sector field mass spectrometer (ICP-SFMS), with reference to ICH Guideline Q2 Validation of Analytical Procedures: Text and Methodology. This method was used in the assessment of twenty-one ( = 21) elements (Al, Au, Ba, Be, Bi, Cd, Co, Cr, Cu, Fe, Hg, Li, Mg, Mn, Mo, Pb, Pt, Sn, Ti, Tl, V) to evaluate the safety of thirty-six ( = 36) protein powder samples that were commercially available in the Irish marketplace in 2016/2017. Using the determined concentrations of elements in samples (µg·kg), a human health risk assessment was carried out to evaluate the potential carcinogenic and other risks to consumers of these products.
View Article and Find Full Text PDFBackground: Therapeutic drug monitoring (TDM) for busulfan supports dose adjustment during conditioning for stem cell transplantation. The authors aimed to develop and validate limited sampling strategies (LSS) of 4-5 samples for a precise estimation of the area under concentration (AUC)-time curve of busulfan, in plasma as an alternative to an intensive sampling strategy (ISS) requiring 9-10 samples.
Methods: ISS TDM data from 297 patients (≤18 years of age) were used.