Early detection of cancer biomarkers is crucial for effective diagnosis and treatment, prompting the development of an ultrasensitive label-free electrochemical immunosensor. In this study, we fabricated an ultrasensitive label-free electrochemical immunosensor using a glassy carbon electrode/gold nanoparticles (GCE/AuNPs) modification for quantification of osteopontin (OPN), an oncomarker. The surface features of the modified electrodes were confirmed using scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) methods.
View Article and Find Full Text PDFObjective: To identify the COVID-19 pandemic impact on well-being/mental health, coping strategies, and risk factors in adolescents worldwide.
Method: This study was based on an anonymous online multi-national/multi-language survey in the general population (representative/weighted non-representative samples, 14-17 years of age), measuring change in well-being (World Health Organization-Five Well-Being Index [WHO-5]/range = 0-100) and psychopathology (validated composite P-score/range = 0-100), WHO-5 <50 and <29, pre- vs during COVID-19 pandemic (April 26, 2020-June 26, 2022). Coping strategies and 9 a priori- defined individual/cumulative risk factors were measured.
Background: Lung cancer remains a leading cause of cancer-related deaths globally, with increasing incidence among females. Sex differences in lung cancer risk and outcomes are influenced by various factors, including biological characteristics. In Bangladesh, where lung cancer mortality rates are high, patients often present at advanced stages.
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