Publications by authors named "G H Mcclelland"

Context: Individual variability in oral vitamin D supplement response hinders the understanding of its clinical impact, and while ethnicity has been implicated in this variability it has not been well described.

Objective: The aim was to systematically assess the impact of ethnicity on response to oral vitamin D supplementation.

Data Source: The Web of Science and PubMed databases were searched for articles published from 1960 to the end of 2020.

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Article Synopsis
  • * Utilizing data from 26 studies published between 1990 and 2019, the results revealed that about 55% of suspected onychomycosis cases were confirmed through PCR analysis, with dermatophytes being the most common infective organisms; specific groups like females and residents of arid countries showed unique trends.
  • * It was found that 90% of countries assessed lacked access to the most effective topical treatments, with Africa facing the greatest access challenges, highlighting a significant global issue in the availability of effective therapies for fungal infections. *
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Objectives: To explore the acceptability and feasibility of detection of atrial fibrillation (AF) by emergency medical services (EMS) and identify potential barriers and facilitators to implementing a formal pathway to facilitate follow-up in primary care, which could reduce the risk of AF-related stroke.

Design: Qualitative study using focus groups and one-to-one interviews guided by a semistructured topic guide.

Setting: North East England.

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Introduction: Large-vessel occlusion (LVO) stroke is effectively treated by time-critical thrombectomy, a highly specialised procedure only available in a limited number of centres. Many patients with suspected stroke are admitted to their nearest hospital and require transfer to access treatment, with resulting delays. This study is evaluating the accuracy of a new rapid portable test for LVO stroke which could be used in the future to select patients for direct admission to a thrombectomy centre.

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