How Do Home Care Workers Experience A Client's Death, Professionally and Personally? A Systematic Review and Meta-Synthesis.

Home care workers (HCWs) may frequently experience client death. This critical interpretive meta-synthesis aimed to identify the impacts of client death to offer preliminary recommendations with respect to support. Five electronic databases, APA PsycINFO, CINAHL, MEDLINE, Web of Science, and Scopus, were searched systematically using keywords and subject headings.

Proteomic and functional comparison between human induced and embryonic stem cells.

Human induced pluripotent stem cells (hiPSCs) have great potential to be used as alternatives to embryonic stem cells (hESCs) in regenerative medicine and disease modelling. In this study, we characterise the proteomes of multiple hiPSC and hESC lines derived from independent donors and find that while they express a near-identical set of proteins, they show consistent quantitative differences in the abundance of a subset of proteins. hiPSCs have increased total protein content, while maintaining a comparable cell cycle profile to hESCs, with increased abundance of cytoplasmic and mitochondrial proteins required to sustain high growth rates, including nutrient transporters and metabolic proteins.

An orphan gene is essential for efficient sperm entry into eggs in .

Unlabelled: While spermatogenesis has been extensively characterized in the model system, very little is known about the genes required for fly sperm entry into eggs. We identified a lineage-specific gene, which we named ( ), that is required for efficient fertilization. Males that do not express produce and transfer sperm that are stored normally in females, but sperm from these males enter eggs with severely reduced efficiency.