Publications by authors named "G H FLETCHER"
Article Synopsis
- The study investigates the prevalence and impact of Human pegivirus-1 (HPgV-1) in Indian individuals living with HIV, as there is limited research on this topic.
- Among 347 HIV treatment-naïve participants, 11% tested positive for HPgV-1, while only 1% of 100 healthy controls did; HPgV-1 genotype-2a was primarily found in those with HIV.
- The research indicates a correlation between HPgV-1 viral load and CD4+ T-cell counts, hinting at HPgV-1's potential influence on HIV disease progression, though further longitudinal studies are necessary for a clearer understanding.
Over the course of the past two decades, attrition within the US governmental public health workforce has passed concerning and become dire. The practice sector has struggled to recruit and retain new talent, despite the infusion of considerable federal investment in workforce expansion initiatives. In 2020, Emory University's Rollins School of Public Health partnered with the Georgia Department of Public Health to establish the Rollins Epidemiology Fellowship Program.
View Article and Find Full Text PDFThe nature of vaccine response inferiority is not well studied in children living with HIV (CLHIV). The authors investigated Hepatitis B Virus (HBV) and Diphtheria/Pertussis/Tetanus toxoid (DPT) vaccination responses following primary immunization in CLHIV (n = 42) and healthy controls (HC) (n = 38) and the effect of an additional vaccine dose. Antibody responses, CD4 and HBV-specific T/B cells were analysed using CMIA/ELISA and flow-cytometry.
View Article and Find Full Text PDFIn the dynamic landscape of scientific research, imaging core facilities are vital hubs propelling collaboration and innovation at the technology development and dissemination frontier. Here, we present a collaborative effort led by Global BioImaging (GBI), introducing international recommendations geared towards elevating the careers of Imaging Scientists in core facilities. Despite the critical role of Imaging Scientists in modern research ecosystems, challenges persist in recognising their value, aligning performance metrics and providing avenues for career progression and job security.
View Article and Find Full Text PDFArticle Synopsis
- Norovirus is the main cause of viral gastroenteritis worldwide, mainly spreading through person-to-person contact and contaminated food, especially shellfish.
- This study aims to assess norovirus infectivity in shellfish using reverse transcription quantitative PCR (RT-qPCR) and a specific dye (PMAxx-RT-qPCR) to analyze viral integrity after high-pressure processing (HPP).
- Results showed increasing non-infectious virus ratios with higher pressure and temperature conditions, indicating that high-pressure treatments can reduce the integrity and infectivity of norovirus in shellfish.