Publications by authors named "G Gutjahr"
Background: The aetiology of congenital heart disease (CHD) is multifactorial. Environmental risk factors have emerged as an important modifiable determinant of several congenital cardiac conditions. Previous studies have shown a strong relationship between CHD and air pollution.
View Article and Find Full Text PDFAdopting a model of antimicrobial stewardship program to anti-tubercular treatment stewardship: A single-centre experience from a private tertiary care hospital in South India.
PLoS One
November 2024
Tuberculosis (TB) remains a significant public health challenge in Low- and Middle-Income Countries (LMIC). Inappropriate use of Anti-Tubercular Treatment (ATT) undermines treatment efficacy and could contribute to drug resistance. While antimicrobial stewardship programs (AMSP) are well established, anti-tubercular treatment stewardship programs (ATTSP) in private hospitals do not have an established model.
View Article and Find Full Text PDFDeveloping Augmented Pro-SOFA and Pro-SAPS Models by Integrating Biomarkers PCT, NLR, and CRP with SOFA and SAPS-III Scores.
Indian J Crit Care Med
October 2024
Background: Sepsis, a life-threatening condition characterized by a dysregulated immune response to infection, remains a significant clinical challenge globally. This study aims to enhance the predictive accuracy of existing sepsis severity scores by developing augmented versions of the SOFA and SAPS-III models, termed Pro-SOFA and Pro-SAPS, through the integration of biomarkers procalcitonin (PCT), neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP).
Methods: This prospective observational study was conducted in the medical ICU of a tertiary care hospital in southern India from August 2022 to December 2023.
Article Synopsis
- * Conducting a retrospective cohort study, researchers tracked 3,256 patients from a cancer institute with a median follow-up of 8.1 years, finding 5-year and 10-year survival rates for various types of breast cancer.
- * The results indicated that poorer survival rates correlated with factors like advanced tumor stages, nodal involvement, negative estrogen receptor status, and high Ki67 index, yet the overall survival rates of these Indian patients were similar
Background: Coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a life-threatening fungal infection. Studies focusing on CAPA in low- and middle-income countries are limited.
Methods: This retrospective matched case-control study was conducted at a tertiary care center in South India.