Matrix Metalloprotienases and its inhibitors: An insight.

Periodontal disease progression involves degradation of the collagenous matrix by a group of enzymes known as the matrix metalloprotienases. These matrix metalloprotienases are secreted by the polymorphonuclear leukocytes, macrophages, fibroblasts, bone, epithelial and endothelial cells. These molecules have involvement in both physiological and pathological processes.