Heat shock protein (HSP) and its correlation to cocaine-related death: a systematic review.

Background: Investigating deaths related to chronic cocaine abuse can be a difficult task, particularly when they occur suddenly and without explanation. Cocaine abuse can trigger biological effects similar to physiological stressors, causing the body to produce heat-shock proteins (HSPs). However, there is still limited information on the specific levels of each HSP type.

Lethal nitrous oxide (NO) intoxication during surgery: the contribution of immunohistochemistry in identifying the cause of death: a case report.

Background: Nitrous oxide (NO) is a gas used in medicine for its analgesic, anxiolytic and amnesic properties. It is a drug considered safe if adequately administered. In the literature, accidental NO-related deaths are rare.

Wound Vitality in Decomposed Bodies: New Frontiers Through Immunohistochemistry.

The question about wound vitality and the estimation of wound age of production are two of the classic investigation fields of forensic sciences. To answer this, the techniques most frequently used in research studies are immunohistochemistry (IHC), molecular biology, and biochemistry. Despite the great data on the literature about the usefulness of IHC in forensic pathology, there is always a request for further studies, especially on tissues altered by putrefactive phenomena.