Publications by authors named "G Guga Priya"
Background: Neurological disorders are a major global health concern, especially in BRICS nations (Brazil, Russia, India, China, South Africa), where demographic and socio-economic changes have amplified their impact. This study evaluates trends in incidence, prevalence, mortality, and Disability-Adjusted Life Years (DALYs) associated with neurological diseases in these countries from 1990 to 2021, focusing on sex disparities and key risk factors.
Methods: Data were obtained from the Global Burden of Disease (GBD) 2021 database.
Introduction: Although spp., including , have emerged as important zoonotic foodborne pathogens globally, the understanding of the genomic epidemiology of of porcine origin is limited.
Methods: As pigs are an important reservoir of , we analyzed genomes that were isolated ( = 3) from pigs and sequenced (this study) them along with all other genomes for which pig intestines, pig feces, and pigs were mentioned as sources in the NCBI database up to January 6, 2023.
Article Synopsis
- - Glucocorticoid (GC) therapy can effectively treat serious inflammatory disorders but carries risks of side effects, requiring the lowest effective dose for the shortest duration to minimize these risks.
- - Tapering GC therapy is crucial to avoid adrenal insufficiency by allowing the hypothalamic-pituitary-adrenal (HPA) axis to recover while monitoring for disease reactivation; higher doses can be tapered quickly, but once close to physiologic doses, tapering must slow down.
- - Patients on GCs need to be aware of potential adrenal crisis during illnesses and should increase their doses accordingly while carrying a steroid alert card to inform healthcare providers.
Article Synopsis
- Liver abscess is a serious medical emergency requiring immediate treatment, often involving both antimicrobial therapy and drainage procedures.
- In a clinical trial, 140 participants were treated with either Ciprofloxacin or Cefixime alongside Metronidazole, both showing high clinical cure rates (89.3%) over the course of 8 weeks.
- Cefixime resulted in fewer treatment failures due to persistent issues compared to Ciprofloxacin, highlighting its potential as a preferred option for treating uncomplicated liver abscesses, warranting further research.
Article Synopsis
- * A new diagnostic method called single-tube nested PCR (STN-PCR) has been developed to detect the virus, using specially designed primers for better sensitivity and lower contamination risks.
- * The STN-PCR assay showed a 100-fold improvement in detecting the virus compared to traditional methods, successfully identifying 100 copies of ASFV genomic DNA, and demonstrated 100% specificity with strong agreement with existing assays.