Publications by authors named "G Guemkam"
Article Synopsis
- This study focused on the prevalence and types of childhood nephrotic syndrome in Africa, highlighting its significant impact if untreated, leading to serious health issues.
- The research included data from 81 studies across 17 countries, finding that 64% of the 8,131 children were steroid-sensitive, while 34% were steroid-resistant, with common pathological diagnoses being minimal change disease and focal segmental glomerulosclerosis (FSGS).
- The results emphasize a lack of comprehensive data on childhood nephrotic syndrome in Africa, which hinders effective healthcare resource allocation for this treatable condition.
Long-term outcomes of early initiated antiretroviral therapy in sub-Saharan children: a Cameroonian cohort study (ANRS-12140 Pediacam study, 2008-2013, Cameroon).
BMC Pediatr
April 2021
Background: In most studies, the virological response is assessed during the first two years of antiretroviral treatment initiated in HIV-infected infants. However, early initiation of antiretroviral therapy exposes infants to very long-lasting treatment. Moreover, maintaining viral suppression in children is difficult.
View Article and Find Full Text PDFEarly treated HIV-infected children remain at risk of growth retardation during the first five years of life: Results from the ANRS-PEDIACAM cohort in Cameroon.
PLoS One
March 2020
Background: Long-term growth in HIV-infected infants treated early in resource-limited settings is poorly documented. Incidence of growth retardation, instantaneous risk of death related to malnutrition and growth parameters evolution during the first five years of life of uninfected and early treated HIV-infected children were compared and associated factors with growth retardation were identified.
Methods: Weight-for-age (WAZ), weight-for-length (WLZ), and length-for-age (LAZ) Z-scores were calculated.
Low rate of early vertical transmission of HIV supports the feasibility of effective implementation of the national PMTCT guidelines in routine practice of referral hospitals in Cameroon.
Paediatr Int Child Health
August 2019
: Vertical (VT) transmission of HIV remains a public health concern in sub-Saharan Africa. : To investigate the VT rate and factors associated with transmission in routine practice in three referral hospitals in Cameroon. : All HIV-infected mothers who delivered in maternity wards or sought paediatric services during the first postnatal week from November 2007 to October 2010 were invited to participate in the ANRS-Pediacam cohort.
View Article and Find Full Text PDFObjective: HIV infection is associated with cognitive impairments, but outcomes are poorly explored in children starting antiretroviral therapy (ART) early or in those exposed but uninfected.
Design: Nested cross-sectional evaluation of the neurocognitive and behavioural outcomes of HIV-infected, HIV-exposed uninfected (HEU) and HIV-unexposed (HUU) Cameroonian children at age 4-9 years prospectively followed.
Methods: Cognitive development was assessed in 127 HIV-infected, 101 HEU, 110 HUU children using the KABC-II, neurologic dysfunction using the Touwen examination and behavioural difficulties using the Strength and Difficulties Questionnaire (SDQ).