Publications by authors named "G Guazzotti"
Background: Nocturnal hypoxemic burden has been shown to be a robust, independent predictor of all-cause mortality in patients with heart failure and reduced ejection fraction (HFrEF) and to occur in a severe form even in patients with low or negligible frequency of respiratory events (apneas/hypopneas). This suggests the existence of two components of hypoxemic burden: one unrelated to respiratory events and the other related. The aim of this study was to characterize these two components and to evaluate their prognostic value.
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- Advanced heart failure (AdvHF) presents treatment difficulties, especially when options like mechanical support or transplants are not available, emphasizing a lack of solid medical management evidence.
- A study of 406 AdvHF patients receiving nightly sodium nitroprusside (SNP) infusions revealed no significant hypotension-related discontinuation, and a notable increase in blood pressure was observed after treatment.
- While the combination of SNP and dobutamine led to more weight loss, it also caused a higher rise in creatinine levels, suggesting a balance between effectiveness in improving patient outcomes and potential side effects.
Background: Heart failure is the most common cardiovascular complication of chronic kidney disease (CKD) and foreshadows a high morbidity and mortality rate. Baroreflex impairment likely contributes to cardiovascular mortality. We aimed to study the associations between CKD, heart failure, and baroreflex sensitivity (BRS) and their association with cardiovascular outcomes.
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- The study investigates how changing positions affects functional residual capacity (FRC) in heart failure patients with Cheyne-Stokes respiration (CSR), focusing on the potential worsening of sleep apnea severity when lying on the back compared to the side.
- Eighteen heart failure patients with CSR underwent tests to measure FRC in different positions and showed significant reductions in FRC when switching from sitting to supine, and a partial recovery when moving to lateral positions.
- The findings suggest that lying supine can worsen respiratory issues during sleep, as reduced FRC is linked to increased apnea events, supporting the theory that body position impacts respiratory control in these patients.
As members of the plant microbiota, arbuscular mycorrhizal fungi (AMF) may be effective in enhancing plant resilience to drought, one of the major limiting factors threatening crop productivity. AMF host their own microbiota and previous data demonstrated that endobacteria thriving in modulate fungal antioxidant responses. Here, we used the - Glomeribacter gigasporarum system to test whether the tripartite interaction between tomato, and its endobacteria may improve plant resilience to combined water/nutrient stress.
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