Publications by authors named "G Guarnotta"
Trends and incidence of reported events associated with ureteral stents: an analysis of the food and drug administration's manufacturer and user facility device experience (MAUDE) database.
World J Urol
September 2024
Article Synopsis
- * A total of 2,652 reports were collected over 10 years, showing a rise in reported events, with 31% classified as injuries, 68% as malfunctions, and 4 reports of death; major issues included stent breakage and difficulties during insertion or removal.
- * The findings indicate that breakage, material problems, and insertion difficulties are the most common complications, with some stents, particularly Resonance, having a higher risk of problems compared to others. *
Article Synopsis
- - The study aimed to evaluate the role of the post-void residual (PVR) ratio in achieving a favorable trifecta outcome in patients with lower urinary tract symptoms and benign prostatic enlargement who undergo transurethral resection of the prostate (TURP).
- - A total of 143 patients were analyzed, with key assessments including international prostate symptom score (IPSS), uroflowmetry, and prostate volume measurements; 58% of patients achieved a positive trifecta outcome based on specific postoperative criteria.
- - The research concluded that while preoperative IPSS and maximum urinary flow rate (Qmax) are significant predictors of a successful trifecta outcome, the PVR ratio did not demonstrate independent predictive value.
Background: Phosphodiesterase 5 inhibitors (PDE5i) are the standard medical treatment for erectile dysfunction. Aim of our study was to evaluate the rate of major adverse cardiovascular events (MACE) reported during PDE5i treatment based on Eudra-Vigilance (EV) reports.
Methods: EV database is the system for managing and analyzing data on suspected adverse reactions to medicines which have been authorized or being studied in clinical trials in the European Economic Area.
Article Synopsis
- The study aimed to analyze real-life data on adverse events (AEs) associated with alpha-blockers, focusing on neuro-vascular and sexual side effects reported in the Eudra-Vigilance database.
- Results indicated varying numbers of AEs linked to different alpha-blockers, with tamsulosin showing the highest number at 11,086 incidents, and silodosin having a significantly higher risk of ejaculatory disorders compared to alfuzosin.
- The conclusions suggested that alfuzosin is the safer option for ejaculatory issues, while both silodosin and tamsulosin present lower risks for orthostatic hypotension, emphasizing the need for clinicians to consider these findings when prescribing.
Background: Aim of our study was to assess the impact of vacation on urinary symptoms in health care workers.
Methods: Between March 2018 to October 2019 a survey was carried out by enrolling health care system workers in three centers. Demographic and clinical characteristics of health care workers (i.