The effect of phenolic compounds of poplar leaves extract on cutaneous angiogenesis reaction induced in mice by human mononuclear leukocytes.

The influence of ether fraction of water-soluble extract of poplar leaves (Populus nigra L.) and nine phenolic acids (cinnamic and benzoic acids derivatives) on human mononuclear (MNL) leukocytes angiogenic activity was studied. Ether fraction, containing mainly phenolic acids, increased cutaneous angiogenesis induced in mice by human MNL isolated from the blood of healthy donors.

Isolation and studies of the mutagenic activity in the Ames test of flavonoids naturally occurring in medical herbs.

Quercetin, rhamnetin, isohamnetin, apigenin and luteolin were isolated from medicinal herbs: Erigeron canadensis L., Anthyllis vulneraria L. and Pyrola chloranta L.