Investigating compliance with cow comfort and mastitis control recommendations on mastitis outcomes in smallholder dairy farms in Central Kenya.

A randomized controlled trial was conducted in Kenya in 2020 with the objectives being to assess compliance of smallholder dairy farmers (SDF) with farm-specific mastitis and cow comfort recommendations, to determine factors associated with compliance, and to determine the impact of these recommendations in reducing cases of subclinical mastitis. A total of 114 SDFs (124 cows) were recruited into the study and randomly allocated into intervention (74 farms) and control (40 farms) groups during the first farm visit. Existing farm-level mastitis control and cow comfort strategies were assessed in both intervention and control farms.

Seroprevalence and risk factors associated with infection among calves in Narok County, Kenya.

Background And Aim: East Coast fever (ECF), caused by , is a devastating disease that causes significant economic losses to cattle production in sub-Saharan Africa. Prevention and control of ECF are challenging in pastoral settings due to inadequate epidemiological information. This study aimed to estimate the seroprevalence and risk factors associated with infection among calves in different production systems to help design appropriate control interventions.

In-silico analysis of potent Mosquirix vaccine adjuvant leads.

Background: World Health Organization recommend the use of malaria vaccine, Mosquirix, as a malaria prevention strategy. However, Mosquirix has failed to reduce the global burden of malaria because of its inefficacy. The Mosquirix vaccine's modest effectiveness against malaria, 36% among kids aged 5 to 17 months who need at least four doses, fails to aid malaria eradication.

Alcohol spiked with zolpidem and midazolam potentiates inflammation, oxidative stress and organ damage in a mouse model.

Purpose: Crime-related spiking of alcoholic drinks with prescription drugs is quite common and has been happening for centuries. This study, therefore, evaluated the effects of oral administration of alcohol spiked with the zolpidem and midazolam potent sedatives on inflammation, oxidative stress and various organ damage in male Swiss albino mice.

Methods: Mice were randomly assigned into six treatment groups; the first group constituted the normal control, the second group received 50 mg/kg body weight of zolpidem only, the third group received 50 mg/kg body weight zolpidem dissolved in 5 g/kg alcohol, the fourth group received 50 mg/kg midazolam only, the fifth group received midazolam (50 mg/kg) dissolved in 5 g/kg alcohol and the sixth group received 5 g/kg alcohol.

Randomized control trial to investigate compliance with, and impacts of, cow comfort recommendations on smallholder dairy farms in Kenya.

Smallholder dairy farmers (SDF) in developing countries often have limited understanding on the importance of cow comfort. We conducted a randomized controlled trial with 124 cows on 114 Kenyan SDF to determine the status of cow comfort, to assess compliance to farm-specific cow comfort recommendations, and to evaluate the impacts of the farm-specific interventions on cow comfort. On the first farm visit, stall dimensions and characteristics (e.