Publications by authors named "G Gilberti Vitali"
Background: Frailty, a geriatric syndrome associated with adverse outcomes, lacks a universal definition. No consensus exists on the most effective frailty scale for predicting mortality.
Methods: This prospective observational study followed community-dwelling volunteers for 6 years.
Background: Obesity and frailty are prevalent geriatric conditions that share some pathophysiological mechanisms and are associated with adverse clinical outcomes. The relationship between frailty, obesity, and polymorphism remains inadequately explored. Single nucleotide polymorphisms (SNPs) offer insights into genetic predispositions that may influence the development of both frailty and obesity.
View Article and Find Full Text PDFArticle Synopsis
- Acute sarcopenia is a rapid decline in muscle mass and function in older adults after events like illness or surgery, affecting 28% to 69% of hospitalized patients but often goes undiagnosed.
- Key factors contributing to acute sarcopenia include systemic inflammation, endocrine imbalances, and anabolic resistance, with interventions like early mobilization, resistance exercises, and nutritional support showing promise.
- Future research should focus on continuous muscle assessments, finding biomarkers, and a team approach to manage sarcopenia effectively, emphasizing the importance of early interventions to prevent long-term disability.
Article Synopsis
- Obesity is a significant risk factor for knee osteoarthritis (OA), and this pilot study investigates the impact of a Very Low-Calorie Ketogenic Diet (VLCKD) on obese women with symptomatic knee OA.
- The study involved 20 participants, where 16 completed the 20-week VLCKD protocol, resulting in a significant reduction in BMI and improvement in knee OA symptoms as measured by various health indices.
- The findings suggest that a VLCKD can effectively aid in weight loss and enhance health outcomes for women with obesity and knee OA, indicating potential for further research.
Article Synopsis
- This study compares outcomes of open liver resection (OLR), laparoscopic liver resection (LLR), and percutaneous thermal ablation (PTA) in elderly patients (≥70 years) with single hepatocellular carcinoma (HCC) ≤30 mm.
- A total of 239 patients were analyzed, revealing that PTA resulted in shorter hospital stays and less morbidity than OLR or LLR, but lower 5-year overall and disease-free survival rates.
- The findings suggest that while PTA is advantageous for specific HCC locations, surgical options (OLR and LLR) offer better long-term survival outcomes for elderly patients.