Minimally invasive ablation of a toxic thyroid nodule by high-intensity focused ultrasound.

HIFU is used in the treatment of cancer (prostate, breast) and uterine fibroma but not yet in TNs. This case report describes the first successful ablation of a toxic TN with HIFU. TSH and radioiodine scan normalization were achieved without complications and maintained for 18 months.

[Lutenyl and menstrual disorders. A hospital study].

The efficacy of nomegestrol acetate in the treatment of menstrual cycle disorders and dysfunctional uterine bleedings was confirmed on 66 cases in this study conducted by three hospital departments. The study also confirmed the perfect clinical tolerance of nomegestrol acetate. One knows that the same is not true with Nortestosterone derivatives which were used up to now in these indications.

[Residual ovarian function after minidoses of estroprogestative agents].

Levels of plasma 17 beta oestradiol, FSH and LH, were carried out on the 7th, 14th, 21st and 28th day of the cycle in three studies in order to evaluate the residual ovarian secretions under the influence of low-dose pills (30 micrograms of ethinyl-oestradiol and 150 micrograms of levonorgestrel). The studies consisted of: a preliminary study involving 5 women under the oestrogen/progestogen pills over more than 1 year; a comparative study of the three first cycles on the same preparation against a control cycle (5 women); a comparative crossover study of one cycle of the minidose oestrogen/progestogen preparation and one cycle of oestrogen/progestogen preparation with 50 micrograms of ethinyl-oestradiol (10 women). The results of these trials show that minidose oestrogen/progestogen preparations have a braking effect on the hypophysio-ovarian axis similar to that exerted by the higher dose pills.

[Effects of progestogens on the metabolism of lipids and carbohydrates. Practical consequences (author's transl)].

Estrogens which are one of the components of contraceptive less than pills greater than are incriminated in many cardiovascular accidents. These occur as a result of metabolic disorders (involving lipids and carbohydrates), of modifications in coagulation factors, etc. The possible influence of progestogens was ignored for a long time.