Publications by authors named "G Gerganov"
Rapidly destructive coxopathy (RDC) is a rare type of coxarthritis marked by swift deterioration of the hip joint. Although its cause remains unclear, several pathophysiological mechanisms are proposed. To comprehensively analyze this poorly understood condition, a literature search was conducted focusing on associations of bilateral RDC and rheumatoid arthritis (RA).
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- Intra-fraction motion management is crucial for the accuracy of Stereotactic Ablative Radiotherapy (SABR), and this study evaluated the effectiveness of automatic tumor segmentation in MR-guided radiotherapy compared to manual delineation.
- Twenty patients with either thoracic or abdominal tumors were analyzed using a combination of experienced observers' manual delineations and four different algorithms for automatic tumor contouring, assessing accuracy through various geometrical analysis metrics.
- Results showed that the automatic segmentation algorithms achieved excellent agreement with manual contours, demonstrating high reliability and accuracy, thereby supporting the use of DIR-based auto-contouring in MRgRT for precise treatment delivery.
Background: Rheumatoid arthritis (RA) increases the risk of cardiovascular disease (CVD), with inflammation playing a key role. Biologic and targeted synthetic drugs used to treat RA can induce systemic immunomodulation and may have pleiotropic effects on vascular function, making it crucial to investigate their impact on CVD risk in RA patients.
Methods: A systematic review of the literature was conducted to investigate the impact of biologic and targeted synthetic treatments approved for RA on various cardiovascular markers, including endothelial function, arterial stiffness, and subclinical atherosclerosis.
This work explores the application of the liquid scintillation counting of polycarbonates for measurement of the activity concentration of radioactive noble gases. Results from experimental studies of the method are presented. Potential applications in the monitoring of radioactive noble gases are discussed.
View Article and Find Full Text PDFPurpose: The purpose of this work is to study the influence of photon energy cuts on the results of positron emission tomography (PET) Monte Carlo (MC) simulations.
Methods: MC simulations of PET scans of a box phantom and the NEMA image quality phantom are performed for 32 photon energy cut values in the interval 0.3-350 keV using a well-validated numerical model of a PET scanner.