Publications by authors named "G Garden"

Article Synopsis
  • The review examines the use of cannabis and cannabinoids for treating sleep disorders, noting that many patients prefer drug-based therapies despite a lack of strong evidence regarding their effectiveness and safety.
  • After analyzing twenty-one recent studies, the review identifies trends such as the rise of minor cannabinoids, decentralized research methods, and the use of objective measures in trials.
  • It emphasizes the urgent need for more rigorous, well-funded clinical trials with longer durations and larger participant groups to provide clearer guidance for clinicians and patients.
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Article Synopsis
  • - The study explores how atmospheric pressure changes during flights can influence insulin delivery from pumps in people with type 1 diabetes, potentially leading to issues like hypoglycaemia.
  • - An in vitro flight simulation mimicking airline conditions revealed that insulin pumps can over-deliver and under-deliver insulin at different stages of flight, particularly significant during emergency decompression scenarios.
  • - Real-world data from pilots using continuous subcutaneous insulin infusion (CSII) showed that insulin levels remained stable with only a small percentage of blood glucose readings falling outside the safe range, indicating effective management while flying.
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Importance: Nonlinear changes in brain function during aging are shaped by a complex interplay of factors, including sex, age, genetics, and modifiable health risk factors. However, the combined effects and underlying mechanisms of these factors on brain functional connectivity remain poorly understood.

Objective: To comprehensively investigate the combined associations of sex, age, genotypes, and ten common modifiable health risk factors with brain functional connectivities during aging.

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Article Synopsis
  • Alzheimer's disease is a complicated illness that develops over many years and is influenced by both our genes and the environment around us.
  • Scientists are exploring how germs might be linked to Alzheimer's, especially after new evidence from research related to COVID-19 and vaccines.
  • A recent online meeting brought experts together to discuss how microbes could affect Alzheimer's, focusing on questions like how they might cause harmful changes in the brain.
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