Publications by authors named "G Ganesh Raja"

Introduction: Rotator cuff (RC) tears are the most common and disabling musculoskeletal ailments among patients with shoulder pain. Although most individuals show improvement in function and pain following arthroscopic rotator cuff repair (ARCR), a subgroup of patients continue to suffer from persistent shoulder pain following the surgical procedure. Identifying these factors is important in planning preoperative management to improve patient outcomes.

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In an era where chemical synthesis of nanomaterial is accounting for the generation of toxic wastes, leading to nanotoxicity, the present work focuses on the extraction of carbon nanodots from available natural sources such as turmeric smoke. The extracted carbon nanodots were characterized and their physical and chemical attributes were confirmed. The antibacterial property of the isolated carbon nanodots was tested against coliforms and oral bacteria.

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In the present study, biopolymer (chitosan and alginate)-reinforced rhamnolipid nanoparticles were prepared and represented as 'ALG-RHLP-NPs' and 'CHI-RHLP-NPs'. The sizes of the nanoparticles ranged from 150 to 300 nm. The encapsulation efficiencies of ALG-RHLP-NPs and CHI-RHLP-NPs were found to be 81.

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Article Synopsis
  • SNP-based association studies have changed the biomedical landscape, focusing on the genetic factors influencing susceptibility to enteric fever, which is caused by Salmonella enterica serovar typhi and paratyphi.
  • A study in the Punjabi population examined the PARK2_e01(-697) polymorphism to see if it was linked to an increased risk of typhoid fever using blood samples from patients and healthy controls.
  • The results showed no significant association between the PARK2_e01(-697) polymorphism and susceptibility to typhoid fever, suggesting that further research with larger sample sizes is needed to better understand its potential role in the disease.
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  • Progressive myoclonic epilepsies (PMEs) are neurodegenerative disorders common in adolescents, leading to symptoms like worsening myoclonus, ataxia, cognitive decline, and dementia.
  • The study explored the genetic basis of PMEs in three Pakistani families, identifying specific variants in the CLN6 gene through Whole Exome Sequencing and validation techniques.
  • Findings show that CLN6 mutations can expand the known phenotypic spectrum of PMEs and highlight the variability in symptoms even among individuals with the same genetic mutation.
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