Publications by authors named "G Gallili"
A very virulent strain of infectious bursal disease virus (IBDVks) was isolated from the bursae of Fabricius of IBDV-affected broiler chickens. Following 43 serial passages in specific pathogen-free embryonated eggs, an attenuated strain was established (IBDVmb). Dosages of IBDVmb in the range 10(2) to 10(4) embryo infective dose of 50% were found to be safe and protective for commercial chicks.
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- Egg drop syndrome (EDS) virus vaccines are typically made using duck eggs, which can be risky due to potential pathogen exposure.
- Researchers developed a subunit vaccine using a specific protein from the EDS virus, which successfully triggered long-lasting antibody production in test subjects.
- Administering two doses of this recombinant protein vaccine led to strong antibody responses without negatively impacting egg production or quality.
Article Synopsis
- Hemorrhagic enteritis virus (HEV) is a turkey virus that causes serious health issues, including immunosuppression and death, making vaccine development crucial.
- Researchers aimed to create a subunit vaccine using a specific protein from HEV, which was successfully expressed in E. coli for testing.
- The study found that vaccination with this recombinant protein effectively protected turkeys from the virus, indicating its potential for safe and effective use as a vaccine.
Infectious bursal disease virus (IBDV) is the causative agent of Gumboro disease, an infectious disease of global economic importance in poultry. One of the most effective types of inactivated IBDV vaccine is produced by infecting young chickens with a virulent strain, sacrificing them and extracting the virus from the bursa of Fabricius. The goal of this study was to produce an effective subunit vaccine against IBDV thereby providing an effective means of combating the disease.
View Article and Find Full Text PDFNewcastle disease (ND) is a worldwide problem with severe economic implications, affecting chickens, turkeys and other birds. Newcastle disease virus (NDV), a member of the Paramyxoviridae group can cause disease of diverse severity in accordance with environmental factors. NDV strains are classified according to their virulence into three categories.
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