Publications by authors named "G GASTALDI"

Diabetes is a well-recognised risk factor for the development of heart failure, with a prevalence higher than 30% in patients with diabetes aged over 60 years. Heart failure often emerges as the primary cardiovascular manifestation in patients with type 2 diabetes and appears to be even more prevalent in type 1 diabetes. In Switzerland, there are approximately 500,000 individuals with diabetes, and the number of affected people has been steadily rising in recent years.

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  • Osteoarthritis is a common degenerative joint condition, especially in older adults, characterized by the breakdown of cartilage leading to pain and disability, influenced by factors like age, obesity, and trauma.
  • Recent research focuses on the use of cell therapy, particularly mesenchymal stem cells, to regenerate cartilage affected by osteoarthritis through co-culture experiments with other stem cells.
  • The study found that mesenchymal stem cells and their secretome significantly enhance the expression of articular cartilage-specific genes and proteins, suggesting their potential as an effective treatment for cartilage regeneration.
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Aim: To evaluate in vitro and in vivo the accuracy of 3D-printed customized transfer devices during indirect bonding technique (IBT).

Methods: A search for articles published in the English language until April 2022 was carried out using PubMed, Web of Science, Scopus, and Google Scholar databases and by applying a specific search strategy for each database to identify all potentially relevant in vivo or in vitro studies. After the removal of duplicate articles and data extraction according to the participants-intervention-comparison-outcome-study design schema scheme, the methodological quality of the included studies was assessed using the Swedish Council on Technology Assessment in Health Care Criteria for Grading Assessed Studies.

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  • The study examined the effectiveness of different attachment types on the accuracy of dental rotational movements in patients using Invisalign clear aligners.
  • The results showed that optimized attachments had the highest median accuracy (70%), followed by rectangular (65%) and no attachments (63%), but these differences were not statistically significant.
  • Age was a predictor of accuracy, with older patients showing decreased effectiveness, highlighting the need for improvements in attachment configurations for better aligner performance.
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