Analysis of Chemical Composition of Long-Chain Linear Alkylbenzenes Using High-Performance Liquid Chromatography Coupled with Microwave Plasma Torch Mass Spectrometry.

Long-chain linear alkylbenzenes (LABs) are essential precursors to produce alkylbenzene sulfonates, which have high surfactant properties and are readily biodegradable, widely used in various detergents. However, an effective and rapid method for the direct analysis and quality control of LAB chemical composition still needs to be improved. This study uses high-performance liquid chromatography coupled with microwave plasma torch mass spectrometry (HPLC-MPT-MS) to analyze the composition of long-chain LABs and quantify nine of these components.

IRE1α/TRAF2/NF-κB pathway promotes apoptosis via regulating inflammatory cytokines and aggravates brain injury after SAH.

Objectives: To investigate the effect of IRE1α/TRAF2/NF-κB pathway on early brain injury.

Methods: An endovascular puncture model of subarachnoid hemorrhage (SAH) was developed and SAH grading was performed. The following groups of experimental animals were randomly assigned: Blank group, Sham group, SAH+ DMSO group, SAH+STF-083010(IRE1α inhibitor) group, and SAH+BAY11-7082(NF-κB inhibitor) group.

Effects of okadaic acid on Pyropia yezoensis: Evidence from growth, photosynthesis, oxidative stress and transcriptome analysis.

The frequent occurrences of harmful algal blooms potentially threaten marine organisms. The phycotoxin okadaic acid (OA) has been globally detected in seawater, however, the knowledge of effects of OA on macroalgae is limited. This study investigated the effects of OA (0.

Global, regional, and national burden of congenital heart disease, 1990-2021: a systematic analysis for the global burden of disease study 2021.

Unlabelled: Congenital heart disease (CHD) is a major birth defect characterized by structural and functional heart abnormalities. This study provides updated estimates of CHD prevalence, mortality, and disability using the Global Burden of Disease (GBD) 2021 database. We examined the age-standardized rates of CHD prevalence, mortality, and disability-adjusted life years (DALYs) from 1990 to 2021, stratified by gender, age group, and region.

Efficacy and safety of pembrolizumab in advanced gastric and gastroesophageal junction cancer: a systematic review and meta-analysis.

Background: Pembrolizumab, a PD-1 inhibitor, has shown potential for treating advanced gastric and gastroesophageal junction (GEJ) cancer. This meta-analysis evaluates its efficacy and safety, alone or combined with chemotherapy, in this population.

Methods: A systematic review and meta-analysis were conducted in accordance with PRISMA guidelines.