[Inferior colliculus stimulation effects in KrushinskiI-Molodkina strain rats].

The effects of the central nucleus of the inferior colliculus chemical and electrical stimulation on the producing and forming the convulsive manifestations, as well as on the organization of sleep, was studied in Krushinskii-Molodkina strain rats, which have an inherited predisposition to audiogenic seizures. Microinjections of quinolinic acid (10 micrograms) or electrical stimulation with 70 Hz frequency produced the paroxysmal manifestations in the form of intensive circular excursions coincident wild running behaviors on the initial nonseizures motor exitation stage of audiogenic seizures. The results suggest that in Krushinskii-Molodkina strain rats the inferior colliculus is involved in the neuronal network, responsible for initiation and realization to the scampering stage of the evoked convulsive reactions to sound.

[The action of ionotropic glutamate receptor channel blockers on effects of sleep deprivation in rats].

The action of non-competitive glutamate receptor antagonists on the effects of sleep deprivation has been studied on Krushinskii-Molodkina rats having an inherited predisposition to audiogenic seizures and Wistar rats deprived to this respond. Two types of glutamate receptor open channels blockers were used: the selective blockers of NMDA-receptors (memantine and IEM-1921) and blockers of mixed type, impacting both on the NMDA- and presumably Ca(2+)-permeable AMPA/kainate receptors (IEM-1754 and IEM 1925). Rats were subjected to 12 hours long sleep deprivation.

[Odontogenic pain syndrome: integrated approach in analgesia].

The article deals with the study of 96 patients (69 women and 27 men) with odontogenic facial pain syndrome. All patients received complex neurodentist examination with radiological assessment of maxillofacial area and additional functional methods. Patients were divided into two groups, 48 patients in each group.

[Raction of dopaminergic and vasopressinergic systems in sleep deprivation in rats].

Six hours sleep deprivation experiments were carried out on rats after threefold injection of D1 dopamine receptor antagonist SCH 39 166. Immunohistochemical study of striatum revealed the increase in D1 and D2 dopamine receptor and glutamate immunoreactive material during the sleep deprivation and 2 h of postdeprivation period. The level of AMPA glutamate receptors increased under the sleep deprivation and decreased in the postdeprivation period.